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Building upon previous studies, the scientists studied the synthesis and breakdown of fats and proteins over 24 hours – an approach that might also be interesting for athletes.
In collaboration with Italian and Austrian colleagues (from the Venetian Institute of Molecular Medicine and the Universities of Padua, Graz, and Trieste) the researchers identified certain processes that are switched on at night by the regulators of the internal clock: “They include, for example, fat storage, glucose metabolism and insulin sensitivity,” explains Henriette Uhlenhaut.
She is group leader at the Institute for Diabetes and Obesity of Helmholtz Zentrum München (IDO) and the Gene Center of LMU.
“If the body’s internal clock gets out of synch, however, it can have serious consequences for the body’s metabolism.
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Circadian clocks are present in all cells of the body, and have a pervasive influence on all aspects of human physiology.
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At the same time, opposing processes such as fatty acid oxidation and protein breakdown are throttled down, according the authors.